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Specialized Unit

Peritoneal Mesothelioma: Surgery and HIPEC

At Quenet-Torrent Institute, we specialize in surgical treatment of peritoneal mesothelioma with complete cytoreduction and HIPEC. In selected patients with epithelioid subtype, this approach offers 5-year survival of 50-70%.

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Our team's track record

World leaders in abdominal oncological surgery

The Quenet Torrent Institute team brings decades of international experience in highly complex oncological surgery, with results published in leading scientific journals and recognition from European surgical oncology societies.

+20,000 Oncological surgeries performed
+500 Cytoreductive surgery + HIPEC procedures
30+ Years of international experience
Top European reference centre in carcinomatosis
Clinical summary

Peritoneal mesothelioma —a rare primary tumour— is treated with complete cytoreduction and HIPEC with cisplatin, achieving 5-year survival rates of 50-70% in epithelioid variants. At Quenet-Torrent Institute (Teknon Barcelona · Memorial Publio Cordón Madrid), the team of Dr. Quenet and Dr. Torrent is a reference centre for this uncommon condition.

What is peritoneal mesothelioma?

Peritoneal mesothelioma is a rare malignant tumor originating from the mesothelial cells that line the peritoneal cavity. It differs from pleural mesothelioma (lung lining) in location, behavior, and prognosis.

There are three main histological subtypes: epithelioid (most common, ~70%, best prognosis), sarcomatoid (worst prognosis), and biphasic (mixed, intermediate prognosis). Subtype is the main determinant of treatment strategy.

While asbestos exposure is a recognized risk factor, 30-50% of cases have no identified cause. BAP1 gene mutations are present in a significant proportion.

In epithelioid cases selected for surgery, cytoreductive surgery with HIPEC achieves median survival of 50-90 months — a dramatic improvement over the approximately 12 months seen without specific surgical treatment.

Why request a second opinion for peritoneal mesothelioma?

This rare tumor requires evaluation by centers with documented experience in this specific condition.

Confirm histological subtype

Confirm whether you have epithelioid, sarcomatoid, or biphasic mesothelioma — the critical factor for treatment eligibility.

Evaluate surgical candidacy

Assess whether complete cytoreduction is technically and oncologically feasible.

BAP1 and molecular testing

Identify genetic mutations that may influence prognosis and treatment selection.

Immunotherapy integration

Evaluate how immunotherapy (nivolumab + ipilimumab) can be integrated into the overall treatment strategy.

In rare tumors like peritoneal mesothelioma, treatment at a specialized center with documented experience is essential.

How do we treat peritoneal mesothelioma?

Treatment depends critically on histological subtype and is planned in a multidisciplinary committee.

Complete cytoreductive surgery

For epithelioid cases: removal of all visible tumor implants and affected peritoneal surfaces.

HIPEC with cisplatin/mitomycin C

Hyperthermic intraperitoneal chemotherapy immediately after cytoreduction to treat microscopic residual disease.

Immunotherapy

Nivolumab + ipilimumab for unresectable cases or as perioperative treatment in selected candidates.

Systemic chemotherapy

Pemetrexed-based regimens for advanced or unresectable disease.

All cases are discussed in a specialized multidisciplinary tumor board to individualize the optimal treatment sequence.

Technology for treating peritoneal mesothelioma

Specialized diagnostic and surgical technology ensures the best possible outcomes in this rare disease.

Automated HIPEC equipment

Precise thermal and flow control during cisplatin/mitomycin C perfusion.

PET-CT and MRI

Detailed preoperative staging to evaluate disease extent and guide surgical planning.

Molecular pathology

BAP1, NF2, and other relevant molecular markers to guide prognosis and treatment decisions.

Expert mesothelioma pathology

Specialist pathologists with experience in this rare tumor for accurate subtype classification.

Reference center for peritoneal mesothelioma

Quenet-Torrent Institute has extensive experience in this rare tumor and is one of the leading centers in Spain for peritoneal mesothelioma treatment.

Experience in Complex Cases

We specialize in treating advanced and metastatic cancer, using innovative techniques that other teams do not offer.

Comprehensive Multidisciplinary Approach

We form a team around you with surgeons, oncologists, radiologists, nutritionists, and psychologists, all working together for your cure.

Research and Innovation

We stay up to date with the latest scientific advances, allowing us to apply innovative treatments with better results.

State-of-the-Art Technology

We have facilities equipped with the most current medical technology, allowing us to perform high-precision procedures with less impact on the body.

Personalized and Close Care

We care about each patient as a person. We listen, support, and guide every step of the way.

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Peritoneal mesothelioma specialists

Every physician at Quenet-Torrent Institute is a recognized expert in their field, committed to each patient's well-being.

Dr. François Quenet

Dr. François Quenet

Oncological Surgeon

View doctor
"Internationally renowned surgeon, expert in gastrointestinal and hepatobiliary tumors. Recognized for his precision in highly difficult surgeries."
Dr. Juan José Torrent

Dr. Juan José Torrent

Oncological Surgeon

View doctor
"Specialist in gynecological tumors and peritoneal carcinomatosis. A reference in complex and personalized oncological surgery."

Where to treat peritoneal mesothelioma?

The Quenet-Torrent team consults and operates in two leading private hospitals in Spain, and welcomes international patients with prior remote case assessment.

Barcelona

Centro Médico Teknon

Carrer de Vilana, 12 · 08022 Barcelona, Spain

  • Consultations with the Quenet-Torrent team
  • High-complexity surgical theatre and HIPEC
  • Reference private hospital in Catalonia
See Barcelona site
Madrid

Memorial Publio Cordón Hospital

Paseo de la Casa de Campo, 5 · 28223 Pozuelo de Alarcón, Madrid, Spain

  • Surgical oncology unit of the Quenet-Torrent team
  • Cytoreductive surgery, HIPEC, PIPAC and robotics
  • High-tech private hospital (2026)
See Madrid site
International

Patients from around the world

We receive patients with peritoneal mesothelioma referred from Europe, Latin America and the Middle East.

  • Remote case assessment by our committee
  • Travel and stay coordination in Spain
  • Care in Spanish, English and French
Submit my case

Frequently asked questions about peritoneal mesothelioma

Answers to the most common questions about diagnosis, treatment, and prognosis.

Is peritoneal mesothelioma the same as pulmonary mesothelioma?

No. Both originate from mesothelial cells, but in different locations. Peritoneal mesothelioma has a better prognosis thanks to the possibility of surgical treatment.

Is peritoneal mesothelioma always caused by asbestos?

No. Although asbestos is a known risk factor, 30-50% of cases have no documented exposure. BAP1 genetic mutations and other factors are involved in a significant.

What is the life expectancy with peritoneal mesothelioma?

With CRS + HIPEC in epithelioid mesothelioma: median survival 50-90 months and 5-year survival 50-70%. Without specific surgical treatment: median survival approximately.

What histological subtypes exist?

Epithelioid (best prognosis, ~70%), sarcomatoid (worst prognosis, surgery not recommended), and biphasic (intermediate). Subtype is the most critical factor in treatment.

What role does immunotherapy play?

Nivolumab + ipilimumab is now first-line treatment for unresectable mesothelioma. Integration with surgery in resectable cases is being studied in clinical trials.

Where can I receive this treatment safely?

In specialized centers with experience in peritoneal mesothelioma, like Quenet-Torrent Institute, one of the leading centers for this condition in Spain.

What our patients say

See on Google ★★★★★
L
Loreto Toscano
4 weeks ago
★★★★★

Wonderful surgical team, among the best out there. Dr. Torrent (expert in peritoneal carcinomatosis) is an exceptional surgeon and an even better person. His coordinator is super kind, fast and efficient. The human treatment is great and the results are too. This is of vital importance for cancer patients.

K
Kanijo Sánchez
5 months ago
★★★★★

In the public healthcare system they gave my father a maximum of one year to live. They only offered him chemo and no hope, said it was impossible, that nothing could be done. He had several tumors inside the peritoneal sac with metastases. A year and a half later he is clean, completely cured. His latest PET scan came back clean. We are very happy. Thanks to Dr. Torrent and his team. THANK YOU.

M
Manuel S.D.
A year ago
★★★★★

Excellent professionals, especially Dr. Torrent, attentive at all times to the patient (my wife), operated for peritoneal pseudomyxoma. They helped us with all our needs since we came from outside Barcelona. Thank you Elisabeth. We are very grateful to Quenet Torrent Institute, thank you for everything.

P
Pilar Garcés
2 years ago
★★★★★

I am a 63-year-old patient. They detected adrenal gland cancer and told me there was nothing to be done. I sought a second opinion and they told me about the Quenet Torrent team, specialists in complex operations. Dr. Torrent, from the first moment, told me they could operate. They operated and removed a large tumor mass. I spent a week in the ICU and a month on the ward. Every day he came morning and evening, no matter Saturday or Sunday. Never throw in the towel. I am happy to have found these professionals who gave me my life back. Thank you.

I
Imma Rondán
3 years ago
★★★★★

Many thanks for your attention. Dr. Torrent always attentive, involved and decisive. The reception staff very pleasant and always offering the best option. 100% RECOMMENDED. THANK YOU.

M
Mª Cristina Domínguez
5 years ago
★★★★★

Dr. Torrent helped me make the best decision at a difficult moment. I think he is a great professional and a person capable of accompanying you and putting himself in another's shoes. Thank you for everything.

F
Francisco García
6 years ago
★★★★★

I have peritoneal carcinomatosis. Sending my diagnosis to every center, practically all agreed on palliative chemo with little survival time since I had very aggressive cell types. Until we reached Dr. Quenet, Dr. Torrent and their team. I can only confirm what their CV announces: they are far ahead of the rest. They saved my life — at surgery the harmful cells everyone diagnosed (and used to refuse to operate) were not there. This intervention has become the best investment of my life.

Where to treat peritoneal mesothelioma?

We operate in two private hospitals of reference in Spain. The same medical team treats you in Madrid and Barcelona, with the same surgical and oncological standards.

Hospital Memorial Publio Cordón, Madrid
Madrid

Memorial Publio Cordón Hospital

Private hospital in Pozuelo de Alarcón with a multidisciplinary team specialised in digestive surgical oncology and cutting-edge surgical technology.

Paseo de la Casa de Campo, 5 28223 Pozuelo de Alarcón, Madrid
View hospital
Barcelona

Centro Médico Teknon

Leading private hospital in Barcelona where the team carries out its high-complexity surgical oncology activity.

Carrer de Vilana, 12 08022 Barcelona
Page coming soon

Patient testimonies and surgery explanations

Real testimonies from patients treated by our team in high-complexity surgical oncology.

Debra's case

66-year-old English woman with advanced ovarian cancer and peritoneal metastases. Treated with cytoreduction + HIPEC, she is now disease-free.

Read the full case

Rosario (Charo)'s case

73-year-old patient with advanced cancer treated with chemotherapy and high-complexity surgical oncology. Excellent survival and quality of life.

Read the full case

Laura's case

Rare abdominal tumor treated with complex cytoreductive surgery plus HIPEC and systemic chemotherapy. Disease-free after almost 2 years.

Read the full case

Santiago's case

Diagnosed with widespread peritoneal carcinomatosis and considered inoperable. After complete cytoreduction with HIPEC, today his is a story of hope and survival.

Read the full case

What our patients say

See on Google ★★★★★
L
Loreto Toscano
4 weeks ago
★★★★★

Wonderful surgical team, among the best out there. Dr. Torrent (expert in peritoneal carcinomatosis) is an exceptional surgeon and an even better person. His coordinator is super kind, fast and efficient. The human treatment is great and the results are too. This is of vital importance for cancer patients.

K
Kanijo Sánchez
5 months ago
★★★★★

In the public healthcare system they gave my father a maximum of one year to live. They only offered him chemo and no hope, said it was impossible, that nothing could be done. He had several tumors inside the peritoneal sac with metastases. A year and a half later he is clean, completely cured. His latest PET scan came back clean. We are very happy. Thanks to Dr. Torrent and his team. THANK YOU.

M
Manuel S.D.
A year ago
★★★★★

Excellent professionals, especially Dr. Torrent, attentive at all times to the patient (my wife), operated for peritoneal pseudomyxoma. They helped us with all our needs since we came from outside Barcelona. Thank you Elisabeth. We are very grateful to Quenet Torrent Institute, thank you for everything.

P
Pilar Garcés
2 years ago
★★★★★

I am a 63-year-old patient. They detected adrenal gland cancer and told me there was nothing to be done. I sought a second opinion and they told me about the Quenet Torrent team, specialists in complex operations. Dr. Torrent, from the first moment, told me they could operate. They operated and removed a large tumor mass. I spent a week in the ICU and a month on the ward. Every day he came morning and evening, no matter Saturday or Sunday. Never throw in the towel. I am happy to have found these professionals who gave me my life back. Thank you.

I
Imma Rondán
3 years ago
★★★★★

Many thanks for your attention. Dr. Torrent always attentive, involved and decisive. The reception staff very pleasant and always offering the best option. 100% RECOMMENDED. THANK YOU.

M
Mª Cristina Domínguez
5 years ago
★★★★★

Dr. Torrent helped me make the best decision at a difficult moment. I think he is a great professional and a person capable of accompanying you and putting himself in another's shoes. Thank you for everything.

F
Francisco García
6 years ago
★★★★★

I have peritoneal carcinomatosis. Sending my diagnosis to every center, practically all agreed on palliative chemo with little survival time since I had very aggressive cell types. Until we reached Dr. Quenet, Dr. Torrent and their team. I can only confirm what their CV announces: they are far ahead of the rest. They saved my life — at surgery the harmful cells everyone diagnosed (and used to refuse to operate) were not there. This intervention has become the best investment of my life.

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