30+ years of experience
500+ CRS+HIPEC procedures
International multidisciplinary committee
Reviewed by Dr Juan José Torrent · Updated: 4 September 2026

Glossary of surgical oncology and peritoneal carcinomatosis

48 terms

The words that appear in a report or during a consultation, explained in plain language for patients and families. Search for a term, filter by area or browse by initial letter.

A

Abdominal CT

Computed tomography, CT scan

Basic imaging test to assess the extent of the tumour and plan surgery. It tends to underestimate carcinomatosis made up of small implants.

Diagnosis and staging

Adjuvant treatment

Treatment given after surgery to destroy any tumour cells that may remain and to reduce the risk of relapse. It is usually chemotherapy and, in some cases, radiotherapy or targeted therapy.

Cancer treatment Go to the page ›

Anastomosis

Surgical join between two ends of bowel, or another conduit, after the diseased segment has been removed. When the join is not considered safe, it is protected temporarily with a stoma.

C

CC score

Completeness of Cytoreduction

Scale that measures how much tumour remains at the end of cytoreductive surgery: CC-0 (no visible residue), CC-1 (nodules smaller than 2.5 mm), CC-2 and CC-3 (larger residue). Achieving CC-0 or CC-1 is the single most important prognostic factor.

Clavien-Dindo classification

International scale that grades postoperative complications according to the treatment they require, from grade I, which needs no intervention, to grade V. It allows results to be compared between centres objectively.

Outcomes and prognosis

Cytoreductive surgery

Cytoreduction

Operation that removes every visible tumour implant from the abdomen, combining organ resections and peritonectomies. It is the backbone of treatment for peritoneal carcinomatosis and is usually combined with HIPEC.

D

Diffusion-weighted MRI

DWI-MRI

Magnetic resonance sequence particularly sensitive to small peritoneal implants. It provides information that CT does not always detect.

Diagnosis and staging

Disease-free survival

DFS

Time that passes without signs of tumour after treatment carried out with curative intent.

Outcomes and prognosis

E

EPIC

Early Postoperative Intraperitoneal Chemotherapy

Intraperitoneal chemotherapy delivered through a catheter during the first days after surgery, without heat. It is used in selected cases, far less often than HIPEC.

Intraperitoneal therapies

ERAS

Enhanced Recovery After Surgery

Protocol of perioperative care (nutrition, early mobilisation, pain control without excess opioids) that shortens hospital stay and reduces complications after major abdominal surgery.

Perioperative care

G

GIST

Gastrointestinal stromal tumour

Rare sarcoma of the digestive tract, with its own treatment combining surgery and targeted therapy. It can spread across the peritoneum.

Conditions Go to the page ›

H

HIPEC

Hyperthermic intraperitoneal chemotherapy

Chemotherapy heated to around 42 degrees and circulated through the abdomen at the end of cytoreductive surgery, to destroy the microscopic tumour cells that surgery cannot see.

Intraperitoneal therapies Go to the page ›

I

Immunotherapy

Treatment that acts on the immune system so that it recognises and attacks the tumour. Its role depends on the tumour type and on specific markers, such as microsatellite instability.

Cancer treatment

Intraoperative radiotherapy

IORT

Single dose of radiotherapy applied directly to the tumour bed during the operation, protecting the surrounding healthy tissue.

Cancer treatment

L

Laparotomy

Open surgery

Surgical approach through an incision in the abdominal wall. It remains the necessary route for extensive cytoreductions and multivisceral resections.

Liver metastases

Tumour deposits in the liver coming from another organ, most often the colon or rectum. Many are operable with curative intent, alone or combined with peritoneal surgery.

Conditions Go to the page ›

Liver resection

Hepatectomy

Removal of the part of the liver involved by the tumour, preserving enough healthy volume for the organ to regenerate.

Lymphadenectomy

Removal of the lymph nodes in the tumour drainage territory, with both therapeutic and staging purposes.

Surgery

M

Malignant ascites

Build-up of fluid in the abdominal cavity caused by tumour disease of the peritoneum. It produces distension, early satiety and breathlessness, and is one of the most frequent reasons for consultation in peritoneal carcinomatosis.

Signs and symptoms Read the full explanation ›

Multidisciplinary team meeting

Tumour board

Meeting in which surgeons, oncologists, radiologists, pathologists and other specialists jointly decide each patient's treatment. In complex surgical oncology it is a quality requirement, not a formality.

Diagnosis and staging Go to the page ›

N

O

Omentectomy

Removal of the omentum, the fatty apron hanging from the stomach and the colon. It is one of the first sites where peritoneal carcinomatosis settles, so it is resected systematically.

Surgery

Oncovascular unit

Team able to resect tumours encasing major vessels and to reconstruct them, which widens operability in cases considered unresectable.

Overall survival

OS

Time elapsed from diagnosis or treatment until death from any cause. It is the principal measure of efficacy in oncology studies.

Outcomes and prognosis

P

PCI

Peritoneal Cancer Index, Sugarbaker index

Score from 0 to 39 that quantifies how much tumour there is in the abdomen and how it is distributed across thirteen regions. It is the reference for deciding whether a complete cytoreduction is achievable.

Diagnosis and staging Read the full explanation ›

Pelvic exenteration

En bloc removal of the pelvic organs involved by the tumour, with the corresponding reconstruction. It is reserved for locally advanced or recurrent tumours, in high-volume centres.

Peritoneal carcinomatosis

Peritoneal metastases

Spread of a tumour across the membrane lining the abdomen, the peritoneum, in the form of multiple implants. It may originate in the colon, rectum, appendix, stomach, ovary, pancreas or the peritoneum itself.

Conditions Go to the page ›

Peritoneal implants

Peritoneal nodules, peritoneal seeding

Tumour deposits on the surface of the peritoneum. Their number, size and location determine the PCI and whether a complete cytoreduction is possible.

Conditions Go to the page ›

Peritonectomy

Removal of the areas of peritoneum involved by the tumour. It may extend to the diaphragm, the pelvis or the paracolic gutters, depending on the map of the disease.

Peritoneum

Thin membrane lining the abdominal wall and the organs it contains. It is the starting point of peritoneal carcinomatosis and the compartment where HIPEC and PIPAC act.

Anatomy

PET-CT

Positron emission tomography

Test combining anatomical and metabolic imaging to detect active tumour foci. In peritoneal carcinomatosis it has limitations for small and mucinous implants.

Diagnosis and staging

PIPAC

Pressurized intraperitoneal aerosol chemotherapy

Aerosolised chemotherapy delivered by laparoscopy and repeatable over several sessions. It is indicated above all when the disease is too extensive for a complete cytoreduction.

Intraperitoneal therapies Go to the page ›

Postoperative morbidity

The set of complications that may appear after surgery. In cytoreduction with HIPEC it is reported in standardised form using the Clavien-Dindo classification.

Outcomes and prognosis

Prehabilitation

Physical, nutritional and psychological preparation in the weeks before major surgery, aimed at reaching theatre in better condition and recovering sooner.

Perioperative care

Pseudomyxoma peritonei

Rare disease in which the abdomen fills with mucinous material, almost always starting from a tumour of the appendix. Its reference treatment is complete cytoreduction with HIPEC.

Conditions Go to the page ›

R

R0, R1, R2 (resection)

Classification of the surgical margin: R0 no tumour at the edges, R1 microscopic involvement and R2 visible residual tumour. It differs from the CC score, which assesses the whole abdomen.

Recurrence

Relapse

Reappearance of the disease after a period of control. In peritoneal carcinomatosis it may be peritoneal, distant or mixed, and it does not always rule out further surgery.

Robotic surgery

Minimally invasive surgery performed with robotic arms controlled by the surgeon, with three-dimensional vision and greater precision in narrow spaces such as the pelvis. It is used above all in rectal and colon cancer.

S

Salvage surgery

Rescue surgery

Operation indicated when previous treatment, surgical or oncological, has failed to control the disease or has left sequelae. It requires teams experienced in complex reconstruction.

Second opinion

Review of the diagnosis and treatment plan by a team other than the one that proposed it. It is especially relevant when a tumour has been described as inoperable.

Care pathway Go to the page ›

Staging

Process of establishing the true extent of a tumour before treating it, using imaging, tumour markers and, in peritoneal carcinomatosis, laparoscopy. A correct surgical indication depends on it.

Diagnosis and staging Go to the page ›

Staging laparoscopy

Diagnostic laparoscopy

Examination of the abdomen with a camera, through millimetre incisions, to see the true extent of peritoneal carcinomatosis and take biopsies before deciding on treatment.

Diagnosis and staging Read the full explanation ›

Stoma

Ostomy, colostomy, ileostomy

Opening of the bowel onto the abdominal wall to divert transit into a bag. It may be temporary, to protect an anastomosis while it heals, or permanent.

Systemic chemotherapy

Drug treatment given intravenously or orally that acts throughout the body. It is complementary to, not an alternative to, therapies directed at the peritoneum.

Cancer treatment

T

TNM

International system that classifies tumours according to size and local invasion (T), lymph node involvement (N) and the presence of distant metastases (M).

Diagnosis and staging

Tumour markers

CEA, CA 19-9, CA 125

Substances measurable in blood that give an indication of a tumour's activity and of its response to treatment. They cannot diagnose on their own and must be interpreted alongside imaging and clinical findings.

Diagnosis and staging Read the full explanation ›

No term matches your search.

This glossary is intended as general information: it helps in understanding a report or a conversation with the medical team, but it does not replace a specialist assessment of an individual case.

Need to speak with a specialist?

Complete the form and schedule your appointment to speak directly with the surgeon.

Request consultation