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Specialized Unit

Pseudomyxoma Peritonei: Surgery and HIPEC

At Quenet-Torrent Institute, we are experts in treating pseudomyxoma peritonei, a rare condition that requires highly specialized surgery. We combine complete cytoreduction with HIPEC for optimal results — achieving cure rates above 80% in low-grade cases.

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What is pseudomyxoma peritonei?

Pseudomyxoma peritonei is a rare clinical condition characterized by progressive accumulation of mucinous material in the abdominal cavity. It usually originates from a ruptured appendicular mucinous tumor, although it can also arise from ovarian or other mucinous tumors. It is colloquially known as "jelly belly".

It is a slow-growing condition that can remain indolent for years. However, without treatment, the progressive accumulation of mucin causes compression of abdominal organs, intestinal obstruction, and nutritional deterioration.

Cytoreductive surgery with HIPEC is the treatment of choice and can achieve cure rates above 80% in low-grade cases when complete resection is achieved — making this the most favorable prognosis among all peritoneal malignancies.

Why request a second opinion for pseudomyxoma peritonei?

This rare condition requires management in specialized centers with extensive documented experience.

Confirm histological grade

Confirm histological diagnosis and grade (LAMN vs. mucinous adenocarcinoma), which determines prognosis.

Evaluate resectability

Assess whether complete cytoreduction (CC0/CC1) is technically achievable.

Assess optimal timing

Determine the best time for surgery based on disease burden and growth rate.

Specialized center

Ensure you are treated at a center with proven experience in this rare condition — volume matters significantly.

The surgeon's experience is the most important prognostic factor in pseudomyxoma peritonei.

How do we treat pseudomyxoma peritonei?

Surgical treatment combined with HIPEC is the foundation of potentially curative management.

Complete cytoreductive surgery

Removal of all visible mucinous disease and affected peritoneal surfaces — the most critical factor for cure.

HIPEC

Hyperthermic intraperitoneal chemotherapy to destroy microscopic residual mucinous cells.

Multivisceral resections

Removal of affected organs when necessary: omentum, spleen, gallbladder, portions of bowel, ovaries.

Iterative surgery

Repeat interventions for recurrences when feasible — particularly effective in low-grade disease.

The goal is complete cytoreduction (CC-0/CC-1) to maximize long-term survival.

Technology for treating pseudomyxoma peritonei

Specialized technology is essential in these complex and often lengthy surgeries.

Automated HIPEC equipment

Precise thermal and flow control for optimal intraperitoneal perfusion.

CT and MRI imaging

Detailed preoperative evaluation of disease distribution and extent.

Tumor markers (CEA, CA 19-9)

Serial monitoring for disease follow-up and early detection of recurrence.

Expert pathology review

Specialist pathologists for accurate histological grading — critical for prognosis and treatment planning.

Reference center for pseudomyxoma peritonei

Quenet-Torrent Institute is a reference center for this rare condition with extensive accumulated experience in pseudomyxoma peritonei.

Experience in Complex Cases

We specialize in treating advanced and metastatic cancer, using innovative techniques that other teams do not offer.

Comprehensive Multidisciplinary Approach

We form a team around you with surgeons, oncologists, radiologists, nutritionists, and psychologists, all working together for your cure.

Research and Innovation

We stay up to date with the latest scientific advances, allowing us to apply innovative treatments with better results.

State-of-the-Art Technology

We have facilities equipped with the most current medical technology, allowing us to perform high-precision procedures with less impact on the body.

Personalized and Close Care

We care about each patient as a person. We listen, support, and guide every step of the way.

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Pseudomyxoma peritonei specialists

Every physician at Quenet-Torrent Institute is a recognized expert in their field, committed to each patient's well-being.

Dr. François Quenet

Dr. François Quenet

Oncological Surgeon

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"Internationally renowned surgeon, expert in gastrointestinal and hepatobiliary tumors. Recognized for his precision in highly difficult surgeries."
Dr. Juan José Torrent

Dr. Juan José Torrent

Oncological Surgeon

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"Specialist in gynecological tumors and peritoneal carcinomatosis. A reference in complex and personalized oncological surgery."

Frequently asked questions about pseudomyxoma peritonei

Answers to the most common questions about diagnosis, treatment, and prognosis.

Can pseudomyxoma peritonei be cured?

Yes, especially in low-grade cases with complete cytoreduction. Cure rates exceed 80% at 10 years in favorable cases Outcomes depend on histology, PCI score, and completeness of cytoreduction.

What is the difference between low and high grade?

Low-grade tumors (DPAM/LAMN) have a much better prognosis than high-grade ones (PMCA/mucinous adenocarcinoma). Accurate histological grading is essential before.

How long does the surgery take?

Cytoreductive surgery with HIPEC can last 8-14 hours depending on disease extent, with continuous adjustment based on intraoperative findings of the case.

How long is the recovery?

Hospitalization is usually 10-14 days and complete recovery 2-3 months, though this may vary depending on the extent of surgery performed El equipo valora cada caso.

What if the disease recurs?

Repeat surgeries are possible and can be effective in controlling the disease long-term, particularly in low-grade cases where the disease grows slowly.

Where can I receive this treatment safely?

In specialized centers with extensive experience in pseudomyxoma, like Quenet-Torrent Institute, where hundreds of these procedures have been performed.

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