30+ years of experience
500+ CRS+HIPEC procedures
International multidisciplinary committee

Quenet Torrent Institute: a new therapeutic strategy in oncology

11/10/2024 · Dr. François Quenet

Quenet Torrent Institute: a new therapeutic strategy in oncology

New therapeutic strategy at Quenet Torrent Institute

At Quenet Torrent Institute we treat advanced cancer by combining cytoreductive surgery, intraperitoneal chemotherapy (HIPEC, PIPAC) and treatments adjusted to the profile of each tumour.

Pillars of the new strategy

1. Maximal cytoreductive surgery: Complex resections that used to be considered impossible. See cytoreductive surgery

2. Regional therapies (HIPEC, PIPAC): Chemotherapy delivered directly into the peritoneal cavity, with greater efficacy. See HIPEC and PIPAC

3. Personalised medicine: Treatments based on the molecular profile of the tumour (BRCA, HER2, RAS, etc.)

4. Multidisciplinary approach: Weekly committees with surgeons, oncologists, radiologists and pathologists

5. Advanced technology: Robotic surgery, intraoperative imaging, augmented reality

Results of the new strategy

• Peritoneal carcinomatosis: Median survival of 40-60 months vs 12-18 with chemotherapy alone

• Complex sarcomas: R0 resection rate >85%. See results in sarcomas

• Advanced ovarian cancer: Complete cytoreduction in >80% of cases

Would you like to know whether your case is a candidate for this strategy? We review your tests and explain the options you have. Request an assessment.

Frequently asked questions

The most common questions, answered with specific data.

What is the new therapeutic strategy in oncology?

It is an integrated approach that combines maximal cytoreductive surgery, regional therapies such as HIPEC and PIPAC, personalised medicine based on the molecular profile of the tumour, and weekly multidisciplinary decision-making. The plan is decided case by case according to each patient's clinical situation.

What does maximal cytoreductive surgery involve?

It is oncological surgery that aims to remove all visible tumour disease, including lesions that were previously considered unresectable. It achieves complete resection (R0) rates above 85% in complex sarcomas.

What are the advantages of combining surgery with HIPEC?

Combining cytoreductive surgery with HIPEC makes it possible to apply chemotherapy directly into the peritoneal cavity at high concentration and temperature. In peritoneal carcinomatosis, this strategy can reach median survivals of 40 to 60 months, compared with 12-18 months with systemic chemotherapy alone.

What is personalised medicine in oncology?

It means adapting treatment to the specific molecular characteristics of each patient's tumour, by analysing markers such as BRCA, HER2 or RAS. This approach improves treatment efficacy and reduces unnecessary exposure to drugs that work poorly for that tumour profile.

What is the multidisciplinary committee and what is it for?

It is a weekly meeting in which surgeons, oncologists, radiologists and pathologists review each case together. This way the treatment decision is made by several specialties together and not by a single doctor.

What role does advanced technology play in this strategy?

Robotic surgery, intraoperative imaging and augmented reality make it possible to plan and carry out resections with greater precision. These tools reduce bleeding, improve the identification of oncological margins and lower postoperative complications.

What is PIPAC and when is it used?

PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy) delivers chemotherapy as a pressurised aerosol inside the abdominal cavity by laparoscopy. It is used when complete cytoreduction is not immediately possible, as palliative treatment or as a bridge to later surgery with HIPEC.

Which patients can benefit from this strategy?

Patients with peritoneal carcinomatosis of colorectal, ovarian, gastric or appendiceal origin; with complex sarcomas; with liver metastases; and patients who have been told at other centres that their disease is unresectable. Each case requires an individual multidisciplinary assessment.

What survival is achieved in advanced ovarian cancer with this approach?

With this strategy, our team achieves complete cytoreduction in more than 80% of advanced ovarian cancer cases. Complete cytoreduction is the most important prognostic factor in this disease, and achieving it significantly improves long-term survival.

Can I ask for a second opinion to find out whether I am a candidate?

Yes. Our team assesses cases from anywhere in Spain and abroad. After reviewing the clinical records and imaging, we provide a detailed assessment of the available treatment options and the indication for each one.

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