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Neoadjuvant chemotherapy in colon cancer: what the ELECLA trial shows

The Spanish ELECLA trial, published in ESMO Open with the participation of Dr. Patricia Tejedor, evaluates giving chemotherapy before surgery in locally advanced colon cancer with a proficient mismatch repair (pMMR) molecular profile.

08/07/2026 · Dr. Patricia Tejedor · ESMO Open

Neoadjuvant chemotherapy in locally advanced colon cancer: the ELECLA trial
Dr. Patricia Tejedor

Article written by

Dr. Patricia Tejedor

Co-author of the study, together with the rest of the ELECLA trial Collaborative Group investigators

Quenet Torrent Institute

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The ELECLA trial (ESMO Open, 2026), with the participation of Dr. Patricia Tejedor, shows that neoadjuvant chemotherapy in pMMR locally advanced colon cancer is safe and feasible, reduces tumor volume and improves pathologic features, without increasing surgical complications.

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